In a subgroup analysis of cancer sites, we also found the similar significant adverse association between levels of GAS5 and OS in the following cancers (low/high): HCC (HR = 1.893, 95% CI: 1.103–3.249, P = 0.021, P(H) = 0.902), UC (HR = 1.653, 95% CI: 1.185–2.306, P = 0.003, P(H) = 0.268) and HR for the subgroup of other cancers was 2.641 (95%CI: 1.625–4.204, P < 0.001, P(H) = 0.730). The gene discussed is GAS5; the disease is hepatocellular carcinoma.