One study indicated that NAC1 can form 300–500 kDa complexes in tumor cells (Nakayama et al., 2016), however, limited interaction partners of NAC1 like HDAC4, Miz1 have been reported (Stead and Wright, 2014; Zhang et al., 2017) and it is unclear how they work together. The gene discussed is HDAC4; the disease is neoplasm.