In our hands, XRCC3 316AA and AG alleles yielded statistically significant results: the OR for all neutropenia grade was 1.52 (95% CI: 0.51–4.91) for GA alleles, and the OR for GG+GA was 2.61 (95% CI: 0.91–7.61) P = 0.03. Here, XRCC3 is linked to Decreased total neutrophil count.