SNCA gene encodes the α-synuclein protein and among the important genes that are associated with PD in general, SNCA gene is well-recognized as the main player in PD pathogenesis, in which mutations or rearrangements of SNCA gene are found in those with autosomal dominant PD (Thomas et al., 2011; Klein and Westenberger, 2012). Here, SNCA is linked to Parkinson disease.