PRKN and Parkinson disease: Since miR-34b and miR-34c are shown to target multiple genes in PD including PRKN and PARK7 (Miñones-Moyano et al., 2011), SNCA (Kabaria et al., 2015b), MAPT (Wu H. et al., 2013), these miRNAs are potentially useful to detect early dysregulation and onset of PD progression.