CSMD1 and schizophrenia: Recently, a CSMD1 variant (Schizophrenia Psychiatric Genome-Wide Association Study [GWAS] Consortium, 2011) was associated with comparatively reduced cortical activation in the middle occipital gyrus and cuneus, a posterior brain region that supports maintenance processes during performance of a spatial working memory task, and affects general cognitive ability and executive function in healthy persons (Koiliari et al., 2014).