As canonical CD157 is a well-characterised receptor that mediates leukocyte, mesothelial and specific tumor (EOC, MPM) cell adhesion to ECM proteins6,11,15, we conducted parallel studies to explore possible functional differences in the capacity of CD157-001 and CD157-002 to mediate cell attachment to fibronectin (FN), type I collagen (COL1) and vitronectin (VN) using the HeLa transfectant model. This evidence concerns the gene FN1 and neoplasm.