INS and hypertensive disorder: In the HTN w/o therapy group, rs13175330 G allele carriers had significantly higher insulin levels (p = 0.001), HOMA-IR indices (p = 0.002), and ox-LDL levels (p = 0.046) than the AA carriers (Table 3) but significantly lower LDL-cholesterol levels (p = 0.039) and smaller LDL particle sizes (p = 0.003) than the AA carriers.