The expression level of LYVE–1 in tumor tissues of patients with lymph node involvement was similar with that in patients without lymph node involvement (P = 0.354), and the similar results were found for VEGFR–3 (P = 0.631), Podoplanin (P = 0.490), and Prox–1 (P = 0.503). Here, PROX1 is linked to neoplasm.