However, CDO1 TaqMeth value of CN was significantly higher than those of NN (p = 0.0084), and the AUC of CDO1 methylation to discriminate T from CN was 0.71, which is the lowest value compared to those reported to date in the literature for cancers such as breast (AUC, 0.84), esophagus (AUC, 0.91), lung (AUC, 0.87), bladder (AUC, 0.87), and stomach (AUC, 0.95) [8]. The gene discussed is CDO1; the disease is cancer.