RNF213 and Moyamoya disease: Interestingly, the G-G-A-G (p = 0.005), G-A-G-G (p < 0.0001), and G-A-A-G (p = 0.033) (RNF213 4448/4810/4863/4950) haplotypes were associated with moyamoya disease risk in the pediatric group whereas G-A-G-A (p < 0.0001) elevated moyamoya disease risk in the adult group.