HLA-B and malaria: 29 However, the most frequent HLA‐B allele observed in the Mandenkalu, B*35:01:01 (AF = 0.16), has been reported as protective to malaria in Ghana86 and its predicted peptide‐binding profile is similar to that of B*53:01:01,29 which also suggests a protective effect to this disease (this is also the case, although to a lesser extent, for the following 2 most common alleles found in this population, B*15:03:01 (AF = 0.08) and B*78:01:01 (AF = 0.08)).