The genetic association of these NOS3 gene polymorphisms and susceptibility to MS have identified in several studies (AlFadhli, Mohammed & Al Shubaili, 2013; Blanco, Yague, Graus, & Saiz, 2003; Modin et al., 2001; Tajouri et al., 2004). The gene discussed is NOS3; the disease is myeloid sarcoma.