From the obtained results, a positive correlation of parameters like IL-6, CRP, TNFR1, and TNFR2 together with MMP9 and TIMP between the growing diameter of aneurysm and mRNA from tissue or protein levels from blood is obvious, although we also found significant negative correlation of Emilin-1 mRNA in the tissue and protein soluble receptor of IL-6 in the blood, which suggests that the release of inflammatory mediators dramatically increases the degradation of ECM in the aortic wall. The gene discussed is MMP9; the disease is aneurysm.