Moreover, it is well known that IL-23 is involved in Th17 expansion and that DCs when loaded with apoptotic or necrotic tumor cells preferentially expand several Th lymphocytes groups.15 On this basis, we evaluated whether enforced expression of miR-29b in DCs, loaded with either apoptotic or necrotic MM cells, differentially induces expansion of Th17 cells from autologous CD3+ lymphocytes. The gene discussed is IL37; the disease is neoplasm.