The PD-L1 assay used in Checkmate 275 measured PD-L1 tumor cell expression using the 28-8 antibody (Dako PD-L1 IHC kit, Dako North America, Carpenteria, CA, USA) and differed from that in the IMvigor 210 cohort which measured immune cell PD-L1 expression using a different diagnostic antibody and staining protocol. The gene discussed is CD274; the disease is neoplasm.