MDM2 and neoplasm: Since LNT caused tumor growth inhibition through suppressing cell proliferation and promoting apoptosis, proliferation- and apoptosis-related makers and signaling cascades including p53, MDM2, telomerase reverse transcriptase (TERT), nuclear factor-kappa B (NF-κB) p65, c-Myc, Caspase 3, Poly [ADP (ribose)] polymerase 1 (PARP1), B-cell lymphoma-2 (Bcl-2), and phosphorylated extracellular signal-regulated kinase1/2 (p-ERK1/2) were assayed by Western blotting.