In the experimental condition for short-term treatment (1, 5, 15, 30 min) with GN or anti-EGFR-GN, the treatment with GN alone increased the phosphorylations of AKT and ERK1/2, but the treatment with anti-EGFR-GN alone suppressed the phosphorylations of FAK and AKT (Supplementary Figure 4). Here, AKT1 is linked to ganglioneuroma.