We found FcGBP mRNA expression level was higher in HPV-positive HNSCC tissues compared to HPV-negative HNSCC tissues in GSE40774 (p<0.0001), while TGF-β mRNA expression level was lower in HPV-positive HNSCC tissues compared to HPV-negative HNSCC tissues in GSE40774 (p<0.0001) (Figure 2A). Here, FCGBP is linked to head and neck squamous cell carcinoma.