Shi Z [36] further demonstrated the mechanism that DICER could process pre-miR-21 to mature miR-21, while the inhibitor of DICER (AC1MMYR2) blocked its ability for miRNA maturation and further suppressed proliferation, survival, and invasion in glioblastoma, breast cancer, and gastric cancer cells in vivo. This evidence concerns the gene DICER1 and gastric cancer.