APEX1 and cervical cancer: However, no significant associations were observed between the HOGG1 (rs1052133, Ser326Cys), XRCC1 (rs1799782, Arg194Trp; rs25487, Arg399Gln; rs25489, Arg280His), ADPRT (rs1136410, Val762Ala), or APE1 (rs1130409, Asp148Glu; rs1760944, -656TG) polymorphisms and the risk of cervical cancer (Table 2).