In addition, lymph node involvement (HR, 2.35; 95% CI 1.48-3.75; P < 0.001) and solid predominant with mucin production adenocarcinoma (HR, 1.77; 95% CI 1.08-2.90; P = 0.023) were adverse prognostic factors for OS. This evidence concerns the gene MUC5AC and adenocarcinoma.