ACYP2 and hepatocellular carcinoma: In Table 3, we found that the minor allele “T” of rs12621038 in ACYP2 was significantly associated increasing the risk of HCC, based on the genotype model “C/T” in chronic HBV carriers increasing a 2.14-flod risk for inducing HCC compared to the “C/C” genotype (95%CI=1.27-3.62, P=0.004).