MYC and cancer: To examine if implantation of ELAS1-expressing cancer cells prolongs the survival of mice due to the apoptosis-inducing function of ELAS1, we inoculated SAS/Tet-On cells, which expressed Dox-inducible Myc-vector or Myc-ELAS1, into the left side of the tongue of each nude mouse and monitored their weight every 2 or 3 days (Supplementary Figure 8A).