MALAT1, a highly conserved nuclear-abundant lncRNA of approximately 8000 nucleotides, received great interest among lncRNAs since its discovery as an independent prognostic biomarker for early stage metastasising NSCLC, and many studies showed the mechanisms of MALAT1 in regulating gene expression, cell proliferation, invasion, and tumour formation in a broad range of human cancers, including pancreas, breast, colon, liver, oesophageal and prostate cancers [17, 18, 19]. Here, MALAT1 is linked to Familial prostate cancer.