We also detected HOTAIR levels in human melanoma cell lines (A375, A875, SK-MEL-1, SK-MEL-5 and SK-MEL-28) and human epidermal melanocytes (HEMa-LP and HEMn-LP) and found that HOTAIR expression was significantly higher in melanoma cells, especially in A375 and A875 cells (Figure 1D). Here, HOTAIR is linked to melanoma.