Kim et al. found that gene polymorphisms in IL-17 and IL-17R were associated with the end-stage renal disease (ESRD), their study indicated that both IL17E rs10137082 and IL17RA rs4819554 are highly expressed in patients with ESRD, which revealed the relationship between IL-17 and kidney damage [21]. Here, IL17RA is linked to stage 5 chronic kidney disease.