CD4 and Miyoshi myopathy: So the proportions of Treg cells (CD4+CD25highFoxP3+) in peripheral blood were also detected in healthy donors (n = 20) and MM patients (n = 58) by flow cytometric analysis (Figure 4A-4D), the Treg cells in the incipient and relapsed MM patients were significantly higher than healthy donors (3.23 ± 1.69% vs. 2.16 ± 0.71%, p < 0.05; 5.06 ± 2.41% vs. 2.16 ± 0.71%, p < 0.01; Figure 4E), but there was no difference between DS stage A and DS stage B groups (Figure 4F).