A processed lncRNA expression data in ccRCC from TCGA database was acquired from TANRIC database, and analyzed with the limma package of R. About 159 annotated differential expressed lncRNAs were identified including 82 upregulated and 77 down-expressed ones, among which the expression of some well characterized lncRNA such as MALAT1, CRNDE, PVT1 and XIST were upregulated (Figure 1A). The gene discussed is CRNDE; the disease is nonpapillary renal cell carcinoma.