We also found a positive correlation between PVT1 and BMI1, ZEB1 and ZEB2 as well as a negative correlation between miR-200c and PVT1, BMI1, ZEB1 and ZEB2 in our 50 paired renal cancer tissues through RT-PCR, which was consistent with that of the analysis from TCGA Data Portal (Supplementary Figure 4A, 4B). This evidence concerns the gene ZEB1 and renal carcinoma.