Besides, the expression of PVT1 in TCGA Data Portal from starBASE v2.0 (http://starbase.sysu.edu.cn/panCancer.php) showed PVT1 is highly expressed in tumor tissues compared with normal tissues in multiple cancers, such as Bladder urothelial carcinoma (BLCA), Breast invasive carcinoma (BRCA), Colon and Rectal adenocarcinoma (CRC), Head and neck squamous cell carcinoma (HNSC), Chromophobe renal cell carcinoma (KICH), Lung adenocarcinoma (LUAD), Glioblastoma multiforme (GBM) and so on. The gene discussed is PVT1; the disease is lung adenocarcinoma.