PVT1 and familial pancreatic carcinoma: PVT1 was found to function as an oncogene in multiple cancers [9, 20, 21] and overexpression of PVT1 may be a powerful predictor of tumor progression and worse prognosis in a wide range of cancers including non-small cell lung cancer, gastric cancer, bladder cancer, colorectal cancers, pancreatic cancer and so on [10–13, 22–24].