In Addition, we also noticed that two very recent studies showing that pharmacological inhibition of LSD1 has significant anti-tumor effects in MV4-11(MLL-AF4) systemic model and Kasumi-1(RUNX1(AML1)/CBFA2T1(ETO)) xenograft model [4, 27, 32]. The gene discussed is RUNX1; the disease is neoplasm.