There is an even more apparent difference (R2=0.1480; p<0.05) in the degree of tumour stromal TSP1 between the well differentiated Grade 1 tumours (mean TSP1: 17.43%; n=6), than the modestly differentiated Grade 2 classed tumours (mean TSP1: 5.738%; n=32), and the poorly differentiated Grade 3 tumours (mean TSP1: 4.333%; n=6). This evidence concerns the gene THBS1 and neoplasm.