The high expression of Ano1 was associated with a tendency toward a longer OS in breast cancer with the low expression of Ki67 (P= 0.052, Figure 4B), especially in ER-positive (P=0.027, Figure 4D), PR-positive (P=0.024, Figure 4F), or HER2-negative (P=0.006) breast cancer (Figure 4G). The gene discussed is MKI67; the disease is breast carcinoma.