TUSC3 and colorectal carcinoma: A significant increase for TUSC3 methylation was also observed in a larger cohort of CRC patients using MethyLight PCR (ML-PCR) (TU 106.8±13.5 vs. NT 45.9±6.0, *p < 0.0001, Wilcoxon signed rank test, n = 74 cases) (Figure 1B).