According to the different types of molecular abnormalities, eight different molecular subtypes of melanoma have been identified [12]: (a) subtype 1 harbors aberrations in the mitogen-activated protein kinase (MAPK) pathway either by itself or in combination with other pathways, such as the AKT/PI3K and cyclin-dependent kinase (CDK) pathways. Here, AKT1 is linked to melanoma.