CRP and chronic kidney disease: Tac: Tacrolimus, RASi: renin-angiotensin-aldosterone system inhibitor, SBP: systolic blood pressure, DB: diastolic blood pressure, cr: creatinine, UPCR: urine protein to creatinine ratio, TA-proteinuria: time averaged proteinuria calculated as the mean urine protein to creatinine ratio, measured every 3 months during both the trial phase of the study, UACR: urine albumin to creatinine ratio, eGFR: estimated glomerular filtration rate by the equation of CKD-EPI, CRP: C-reactive protein, Hematuria: defined as RBC ≥5 under 400-fold magnification examined by light microscopy.