As a result, we examined in detail the impact of FOXA factors on enhancer regions at the CDH1, CDX2 and EPHB3 genes which are among the signature genes of epithelial colon tumors and which are downregulated in Snail1-expressing LS174T cells (S11 Fig, panels B, C) [27,35,41]. Here, EPHB3 is linked to epithelial tumor of colon.