WDR11 and hypogonadotropic hypogonadism: It is a non-synonymous variant with a MAF of 0.5% in the Finnish population.65, 66 The variant is within the WDR11 gene, which is associated with hypogonadotropic hypogonadism 14 with or without anosmia.67, 68, 69 The clinical features of the disease, such as delayed sexualmaturation,68, 70, 71 suggest that it may be misdiagnosed or comorbid with AN, which may explain its association in the analysis.