MME and cancer: As an example, fish oil, which has among its effects metalloproteinase inhibiting properties, has shown benefit as reported in the literature.10, , , , , , -17 However, the stromal biology of cancers is complex and care in manipulating the tumor stroma is needed as cancer stage, patient selection, and possibly proper timing with chemotherapy may make a polar difference in prognosis.18 As pancreatic carcinosarcomas are rare, no known reports have evaluated for CD10 positivity or mentioned use of any metalloproteinase inhibiting substances, which will need further study.