Furthermore, in prostate cancer, in addition to actin stress fibres, ZNF185 co-localizes with several cytoskeletal-related components, such as focal adhesion sites and filopodia/lamellipodia.81 These data suggest that ZNF185 may act as a novel tumour suppressor gene, having a key role in cancer onset and progression. This evidence concerns the gene ZNF185 and prostate cancer.