To investigate whether predictive value of XRCC4 expression for hepatocarcinoma survival was regulated by known clinicopathological features (including age, gender, minority, smoking and drinking status, HBV and HCV infective status, AFP, liver cirrhosis, tumor size, tumor differentiation grade, micro-vessel amount, and BCLC stage), a multivariate survival analysis on the basis of Cox Regression Model (with an Enter Method) was finished (Table 3). This evidence concerns the gene XRCC4 and cirrhosis of liver.