Furthermore, L1CAM expression (≥10%) was observed more frequently in adenocarcinoma (37%) and adenosquamous carcinoma (33%) than in squamous cell carcinoma (15%; squamous cell carcinoma vs. adeno(squamous) carcinoma: OR = 3.2, 95% CI 1.9 – 5.4, P <0.001). The gene discussed is L1CAM; the disease is adenocarcinoma.