L1CAM was shown to be a prognostic factor for overall survival in colorectal cancer, ovarian cancer, neuroendocrine tumors, GIST, cholangiocarcinoma, renal cell cancer, non-small cell lung cancer (NSCLC), hepatocellular cancer, endometrial cancer and for disease-free survival in neuroblastoma, ovarian cancer, neuroendocrine tumors, gallbladder cancer, hepatocellular cancer and endometrial cancer. This evidence concerns the gene L1CAM and cholangiocarcinoma.