We compared nine types of infertility in male humans and mice, including MArrest, oligospermia and teratospermia in humans and Ing2 Knockout (KO), Bcl6 KD, Etv5 KD, Pou3f1 KD, Ikbkap KO and Dazap1 mutant in mice. The gene discussed is BCL6; the disease is Abnormal sperm morphology.