HGF and Cirrhosis: Therefore, in the present study, we overexpressed human HGF (hHGF) in rat-derived primary DPSCs through the transduction of a hHGF-expressing lentiviral vector and evaluated the effects of elevated HGF expression on the survival, fate determination and regenerative capacity of grafted DPSCs in a rat model of cirrhosis to provide an experimental basis for the development of a novel anti-cirrhosis therapy.