For example, transplantation of bone marrow mesenchymal stem cells (BMMSCs) and umbilical cord blood-derived mesenchymal stem cells (UCB-MSCs) overexpressing HGF in a rat model of liver fibrosis was shown to ameliorate liver injury induced by the hepatotoxin carbon tetrachloride (CCl4)20,21. This evidence concerns the gene HGF and Hepatic fibrosis.