DNM3OS and ovarian carcinoma: In TCGA and independent validation (GSE9891) patient cohorts both TWIST1 (Fig. 7a) and DNM3OS (Figs. 1e, 2b) were significantly overexpressed (>twofold change with BH adjusted P < 0.05; TWIST1 in TCGA was determined by edgeR and remaining data were determined by two-tailed t-test) in the mesenchymal subtype compared with the epithelial subtype of ovarian cancer.