TBK1 and amyotrophic lateral sclerosis: A follow-up study of 51 genes in an independent sample of 1318 cases and 2371 controls identified TBK1 as a novel ALS risk gene [9] (discovery association p = 1.13 × 10−5, replication p = 5.78 × 10−7 and combined p = 3.63 × 10−11), with later GWAS support for association of common single nucleotide polymorphisms (SNPs) in the same locus (p = 6.6 × 10–8) [10].