In breast cancer, Hi-C and GWAS have been combined to identify risk loci, including the protein-coding genes IGFBP5, KLF4, NSMCE2, and MYC, and the lncRNAs DIRC3, PVT1, and CCDC26, which are associated with CTCF [92, 93]. The gene discussed is CTCF; the disease is breast carcinoma.