4C-seq with GWAS was used to identify a risk locus for prostate cancers (LNCaP and C4-2B cells), and MYC and POU5F1B were ranked the highest, followed by CD96, PVT1, GSDMC, CXorf36, RRP12, USP14 and SMIN3, which may exhibit abnormal chromatin looping [91]. The gene discussed is MYC; the disease is prostate cancer.