To probe the functional relevance of the co-variations disclosed by analysis of glioblastoma tissues and single cells transcriptomes, we determined the effect of ARNT2 knockdown on the expression of SOX9, POU3F2 and OLIG2 in independent GBM stem-like cell cultures (6240** and 5706**) distinct from TG1 and TG1-miR. Here, SOX9 is linked to glioblastoma.