BRCA2 gene mutation is the most commonly identified genetic mutation in men and it is also shown to increase the lifetime risk of breast cancer in men by about 5-10% compared to the minimal risk of 0.1% seen in the general population [9].The higher proportion seen in our patients may be due to the inclusion of all cancer types compared to only the breast and ovarian cancers seen in the other studies. The gene discussed is BRCA2; the disease is breast cancer.