SERPINA1 and prostate carcinoma: In addition, It has been shown that α1-AT serum levels get elevated in a number of inflammatory diseases and different types of malignancies such as hepatocellular carcinoma, multiple myeloma, pancreatic carcinoma, prostatic carcinoma, primary carcinoma of the lung, cervical carcinoma, gastric cancer, laryngeal carcinoma, nasopharyngeal carcinoma, breast cancer and colorectal carcinoma [7-13].