We determined the TP53 codon 72 genotype in 130 breast cancer patients: 22.3% (29 of 130) of the patients were homozygous for R/R variant, 28.47% (37 of 130) were heterozygous for R/P and 49.2% (64 of 130) were homozygous for P/P variant. The gene discussed is TP53; the disease is breast cancer.