With the exception of an NF1-RHOT1 fusion that would result in NF1 loss-of-function, the remaining 3 fusions identified (NUP98-KDM5A, DEK-NUP214, ETV6-MECOM) are known to be associated with myeloid malignancies (Supplementary Fig. 19). This evidence concerns the gene MECOM and myeloid neoplasm.