LATS2 and esophageal squamous cell carcinoma: In order to investigate whether the discrepant expression of LATS2 is responsible for the tumorigenesis of ESCC, transfection of LATS2 eukaryotic expression vectors and LATS2 interference vector (named cDNA/pLATS2 and siRNA/LATS2, respectively) was performed in ESCC cell lines.