Downregulation of LATS2 significantly correlated with well histological grade (p = 0.028), lymph node metastasis (p = 0.003) and pTNM clinical stage (p = 0.005), while no significant correlations were observed with other clinicopathological parameters (Table 2). This evidence concerns the gene LATS2 and metastatic malignant neoplasm in the lymph nodes.